Method of producing carboxylic acids

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing sulfur-containing organic compound

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435129, 435136, 435822, C12P 1302, C12P 1100

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active

059324546

ABSTRACT:
The method comprises (1) a carboxylic acid salt providing step comprising permitting a strain of microorganism or a preparation derived from the microorganism to act upon a nitrile to thereby (a) provide at least the corresponding amide which is then hydrolyzed in the presence of a base to provide a salt of the corresponding carboxylic acid or (b) provide a salt of the corresponding carboxylic acid and (2) an electrodialysis step comprising subjecting the carboxylic acid salt provided in the step (1) to electrodialysis to provide the corresponding carboxylic acid and base. Carboxylic acids can be produced without formation of ammonium hydrogen sulfate and other byproducts. The microorganism includes microorganisms of the genera Pantoea and Gordona. The ammonia formed in the step (1) can be reused as a nitrogen source in a nitrile production line.

REFERENCES:
patent: 5034105 (1991-07-01), Berglund et al.
patent: 5166426 (1992-11-01), Jakob et al.
patent: 5763652 (1998-06-01), Kawabe et al.
patent: 5814497 (1998-09-01), Favre-Bulle et al.
patent: 5814508 (1998-09-01), Di Cosimo et al.
APS Computer Abstract JPOABS Japan 08-245495 Kawabe "Production of Carboxylic Acid" , Sep. 24, 1996.

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