Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Patent
1989-09-29
1992-05-12
Doll, John
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
5303871, 5303889, 5303899, 435960, 436547, 436548, A61K 39395, C07K 1528
Patent
active
051126060
ABSTRACT:
The present invention relates to methods of producing an antibody highly specific to a low-molecular weight substance such as amino acids, peptides, amines, steroids, etc. The invention also relates to a process for producing the same by forming a complex of the substance with colloidal metal particles and sensitizing a mammal with the complex. The antibody can be in the form of an antiserum containing the antibody. Since the antibody has a high specificity to the intended low-molecular weight substance, it is useful as a reagent for various immunohistochemical methods and immunoassays.
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Kiyama Hiroshi
Kohno Johji
Shiosaka Sadao
Shiotani Yahe
Tohyama Masaya
Doll John
Hutzell Paula
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