Method of producing an artifical skin

Details Method of producing an artifical skin Method of producing an artifical skin

1987-04-06

1989-11-28

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

Hair or skin

623 66, 623901, A61F 210

Patent

active

048834874

ABSTRACT:
An artifical skin comprising an insoluble atelocollagen sheet and an epidermal cell layer cultured only on one surface of the sheet, and a method of producing the same are disclosed, which method includes the steps of: forming an insoluble atelocollagen sheet; inoculating epidermal cells only on one surface of the atelocollagen sheet; and suspending the atelocollagen sheet in a liquid culture medium to culture the epidermal cells, thereby forming an epidermal cell layer.

REFERENCES:
patent: 4294241 (1981-10-01), Miyana
patent: 4485096 (1984-11-01), Bell
patent: 4495288 (1985-01-01), Jarvis, Jr. et al.
Bell et al., Science 211, 1052, (1981).
Yannis et al., Trans. Am. Soc. Artif. Intern. Ogans. XXVII, 19, (1981).
Gallico et al., N. Eng. J. Med., 448, (1984).

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