Method of producing an amide utilizing a microorganism

Details Method of producing an amide utilizing a microorganism Method of producing an amide utilizing a microorganism

1990-01-02

1993-04-06

Marx, Irene

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing nitrogen-containing organic compound

4352521, 435244, C12P 1302, C12N 120

Patent

active

052003310

ABSTRACT:
The present invention relates to a method of producing an amide which comprises subjecting a nitrile to the action of a microorganism belonging to the genus Rhodococcus and having the ability to hydrate the nitrile, and isolating the resulting amide. The microorganism is highly active to a wide variety of nitriles even at low temperatures and, in addition, the hydration reaction of nitriles has a high selectivity for the corresponding amides. Accordingly, this method ensures the production of amides in high yield without formation of by-products such as corresponding carboxylic acids.

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