Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Reexamination Certificate
2007-04-17
2007-04-17
Solola, Taofiq (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
Reexamination Certificate
active
10499876
ABSTRACT:
The invention relates to a special two-step method for producing amines on the basis of amides by reacting them with halides or hypohalites in an aqueous solution in a Hofmann degradation reaction. The amide is reacted in an alkaline solution and/or suspension with halides or hypohalites and the reaction mixture obtained in step 1 is added to an aqueous alkaline solution having a temperature of at least 40° C.
REFERENCES:
patent: 4590292 (1986-05-01), Blackwell et al.
patent: 5001124 (1991-03-01), Patterson et al.
patent: 5032687 (1991-07-01), Diehl et al.
patent: 5034410 (1991-07-01), Sjogren et al.
patent: 5068428 (1991-11-01), Diehl et al.
patent: 5130441 (1992-07-01), Gluchowski
patent: 5410082 (1995-04-01), Pfirmann
patent: 5698711 (1997-12-01), Palfreyman
patent: 5935978 (1999-08-01), Fenton et al.
patent: 6255326 (2001-07-01), Ashton et al.
patent: 275 971 (1988-07-01), None
patent: 1257097 (1971-12-01), None
patent: 61-271255 (1986-01-01), None
patent: 91/15464 (1991-10-01), None
Org. React. 3, 277-282 (1946), Hauser et al The Hoffman Reaction Aromatic and Heterocyclic Amides.
J. Am. Chem. Soc., 59, pp. 121-125 (1931), Hauser et al “The Removal of HX from Organic Compounds by Means of Bases. III. The Rates of Removal of Hydrogen Bromide from Substituted N-Bromobenzamides and their Relative Ease of Rearrangement in the Presence of Alkali. the Hofmann Rearrangement”.
J. Am. Chem. Soc., vol. 60, 2308-2311 (1937), Crenshaw, Cope, Finkelstein and Rogan The Dioxanates of the Mercuric Halides.
J. Am. Chem. Soc., vol. 61, pp. 618-629 (1939), Bright and Hauser; “The influence of Substituents on the Rates of Composition of the Potassium Salts of Dihyroxamic Acids. The Lossen Rearrangement”.
J.X. Wang et al, J. Chem. Research (S) 1986, pp. 456-457 “Phase-tansfer-catalysed Hydration of Nitriles to Amides induced by Pentacarbonylmanganese Bromide”.
D.E. Welch et al, J. Med. Chem (12), 1969, pp. 299-303 “α,60 ,α-Trifluorotoluamides as Anti-coccidial Agents”.
Diehl Herbert V.
Dürrholz Friedrich
Wenzl Peter
Lanxess Deutschland GmbH
Miller Michael A.
Solola Taofiq
LandOfFree
Method of producing amines does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of producing amines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of producing amines will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3786582