Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof
Patent
1997-01-29
1999-06-15
McKelvey, Terry
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Virus or component thereof
4242041, 4242151, 4242171, A61K 3912, A61K 3913, A61K 3915
Patent
active
059119985
ABSTRACT:
A method for producing novel African Green Monkey Kidney (AGMK) cell lines is taught. These cell lines which are free of viable adventitious microbial agents are useful as substrates for viruses and for the preparation of viral vaccines.
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Journal of General Virology, vol. 57, issued 1981, Lee et al., "Serial Propagation of Astrovirus in Tissue Culture with the Aid of Trypsin", pp. 421-424.
Abstracts of the Annual Meeting of the American Society of Microbiology, 23rd Annual Meeting, issued Mar. 1983, Price et al, "The Use of Serially Propagated Monkey Kidney Cell Cultures for the Preparation of High-Titered Hemagglutinin and/or Complement-Fixing Antigens of the Human Parainfluenza Viruses-Types 1, 2 and 3", p. 299, col. 2, abstract T22.
Biologicals, vol. 23, No. 3, issued Sep. 1995, Horaud, "Viral Vaccines and Residual Cellular DNA", pp. 225-228, see p. 227, col. 1.
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Morbidity and Mortality Weekly Report, vol. 40(16): pp. 1-24, Apr. 27, 1991, (Unnamed Author(s)).
Monroe et al, J. of Virology, Feb., 1991, vol. 65(2): pp. 641-648.
Chanock Robert M.
Kapikian Albert Z.
Potash Louis
Purcell Robert H.
Dyncorp
McKelvey Terry
National Institutes of Health
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