Method of producing a tocopherol product

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D31172

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active

061303437

ABSTRACT:
A process of producing a coated tocopheryl succinate is provided. The process comprises contacting a tocopheryl succinate powder with a solution of a pharmaceutically acceptable binder, said tocopheryl succinate being maintained in a fluidized bed during said contacting by passage of a fluidizing gas through said bed. The solvent is then evaporated from said contacted tocopheryl succinate in said fluidized bed. The temperature of said fluidizing gas when introduced into said bed is sufficiently low, e.g. no higher than about 30.degree. C., such that the bed of tocopheryl succinate remains in a fluidized state during said contacting and said evaporating.

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