Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1994-09-06
1996-12-03
Fleisher, Mindy
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
4351723, C12Q 168, C12N 1509
Patent
active
055807348
ABSTRACT:
Materials and methods for homologous-recombination screening of DNA libraries constructed in a eukaryotic host and methods for homologous-recombination chromosome walking for isolating overlapping DNA sequences for building an extended physical map of a chromosomal region.
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Ma et al. "Plasmid construction by homologous recombination in yeast", Gene 58: 201-216. 1987.
Traver et al. "Rapid screening of a human genomic library in yeast artificial chromosomes for single -copy sequences", Proc. Natl. Acad. Sci. USA 86: 5898-5902. Aug. 1989.
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Rothstein "Targeting, disruption, replacement, and allele rescue: Integrative DNA transformation in yeast" in Guthrie et al. (eds.), Methods in Enzymology, vol. 194, Academic Press, New York, pp. 281-301. 1991.
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Stiles et al. (1981) DNA sequence of a mutation in the leader region of the yeast Iso-1-cytochrome c mRNA Cell 25:277-284.
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Miller Allan M.
Treco Douglas A.
Fleisher Mindy
Priebe Scott David
Transkaryotic Therapies Inc.
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