Method of producing a metal sol reagent containing colloidal met

Details Method of producing a metal sol reagent containing colloidal met Method of producing a metal sol reagent containing colloidal met

1993-02-25

1996-05-07

Housel, James C.

Chemistry: analytical and immunological testing

Involving an insoluble carrier for immobilizing immunochemicals

Carrier is inorganic

427216, 4273881, 4273882, 4273883, 427414, 436518, 436524, G01N 33553

Patent

active

055146023

ABSTRACT:
A method and test kit useful in a wide variety of immunoassay systems. A method of producing metal sol reagents containing metal sol particles of a preselected size is provided. A metal containing solution is reduced under optimized pH conditions to produce metal sol particles of a preselected size, the particles are coated with a coupling compound and then bound with at least one selected immunochemically reactive component. Particles having different immunochemical specificities are also mixed to produce reagents having multiple selected immunochemical specificities.

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