Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical
Reexamination Certificate
2004-06-14
2010-12-07
Joike, Michele K (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing saccharide radical
C435S006120, C435S007310
Reexamination Certificate
active
07846697
ABSTRACT:
A method of producing a low molecular weight organic compound (e.g. a plant or bacteria secondary metabolite) in increased yields involving use of a microorganism cell, which comprises a gene involved in the biosynthesis pathway leading to a low molecular weight organic aglycon compound and a glycosyltransferase gene capable of glycosylating the produced aglycon.
REFERENCES:
patent: 6372461 (2002-04-01), Frost
patent: 2006/0275877 (2006-12-01), Hansen et al.
patent: 2691880 (1993-12-01), None
patent: WO01/07631 (2001-02-01), None
patent: WO01/07631 (2001-02-01), None
patent: WO 01/40491 (2001-06-01), None
patent: WO 01/79520 (2001-10-01), None
patent: WO 03/048375 (2003-06-01), None
patent: WO 03/066836 (2003-08-01), None
patent: WO03/066836 (2003-08-01), None
patent: WO03/066836 (2003-08-01), None
de Roode et al. Why are some alcohols easy to glucosylate with beta-glucosidases while others are not? A computational approach. J. Chem. Soc., Perkin Trans, 2: 2217-2224, 2000.
Solanidine. www.rdchemicals.com.
Moehs et al. oning and expression of solanidine UDP-glucose glucosyltransferase from potato. The Plant J. 11(2): 227-236, 1997.
Priefert et al. Biotechnological production of vanillin. Applied Microbiol. Biotechnol 56:296-314, 2001.
Arend et al. Utilizing genetically engineered bacteria to produce plant-specific glucosides. Biotechnol Bioeng. Sep. 2001;76(2):126-31.
Overhage et al. Biotransformation of eugenol to vanillin by a mutant ofPseudomonassp. strain HR199 constructed by disruption of the vanillin dehydrogenase ( vdh ) gene. Applied Micro. and Biotech. 52(6): 820-828, 1999.
Quiros, L.M., et al.: “Two glycosyltransferases and a glycosidase are involved in oleandomycin modification during its biosynthesis byStreptomyces antibioticus”, Molecular Microbiology, Blackwell Scientific, Oxford, GB, vol. 28, No. 6, Jun. 1998, pp. 1177-1185, XP000858900; ISSN: 0950-382X; p. 1181, right-hand column, paragraph 3—p. 1182, left-hand column, paragraph 1; figures 1, 7.
Raty, K. et al.: “A gene cluster fromStreptomyces galilaeusinvolved in glycosylation of aclarubicin” Molecular and General Genetics, vol. 264, No. 1-2, Sep. 2000, pp. 164-172, XP002304279; ISSN: 0026-8925; abstract.
Sanchez, Cesar, et al.: “The biosynthetic gene cluster for the antitumor rebeccamycin: Characterization and generation of indolocarbazole derivatives” Chemistry and Biology (London), vol. 9, No. 4, Apr. 2002, pp. 519-531, XP002304280; ISSN: 1074-5521; abstract; figures 1,3,4.
Arana, Francisca E.: “Action of a beta-glucosidase in the curing ofVanilla” Food Research, ISSN: 0095-974X, vol. 8, 1943, pp. 343-351, XP009024054 p. 347, paragraph 3—p. 348, paragraph 1 p. 348, paragraph 3; table 2 p. 350, paragraph 4 abstract.
Zheng, Zuoxing, et al.: “Solid-State Bioconversion of Phenolics from Cranberry Pomace and Role ofLentinus edodes.beta.-Glucosidase” Journal of Agricultural and Food Chemistry, vol. 48, No. 3, Mar. 2000, pp. 895-900, XP002267398 abstract; figure 6; table 2 p. 898, col. 2, paragraph 2—p. 899, col. 1, paragraph 4.
Day, A. J., et al.: “Deglycosylation of flavonoid and isoflavonoid glycosides by human small intestine and liver beta-glucosidase activity” FEBS Letters, Elsevier Science Publishers, Amsterdam, NL, vol. 436, No. 1, Sep. 25, 1998, pp. 71-75, XP004258361 ISSN: 0014-5793 abstract; figure 1; table 1 p. 74, col. 1, paragraph 4.
Cicek, Muzaffer et al.: “The aglycone specificity-determining sites are different in 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA)-glucosidase (maize.beta.-glucosidase) and dhurrinase (Sorghum.beta.-glucosidase)” Journal of Biological Chemistry, vol. 275, No. 26, Jun. 30, 2000, pp. 20002-20011, XP002267399 abstract; figure 1 p. 20002, col. 2, paragraph 2—p. 20003, col. 1, paragraph 1.
Bak, S. et al.: “Transgenic Tobacco andArabidopsisPlants Expressing the Two MultifunctionalSorghumCytochrome P450 Enzymes, CYP79A1 and CYP71E1, Are Cyanogenic and Accumulate Metabolites Derived From Intermediates in Dhurrin Biosynthesis” Plant Physiology, American Society of Plant Physiologists, Rockville, MD, US, vol. 123, Aug. 2000, pp. 1437-1448, XP001006399 ISSN: 0032-0889 cited in the application abstract; figure 1 p. 1440.
Tattersall, DB et al, “Resistance to an Herbivore Through Engineered Cyanogenic Glucoside Synthesis,” Science; Sep. 7, 2001; vol. 293; pp. 1826-1828.
Rao, SR et al, “Review Vanilla flavour: production by conventional and biotechnological routes,” Journal of the Science of Food and Agriculture; May 11, 2000; vol. 80, No. 3; pp. 289-304.
Paquette, S. et al, “On the origin of family 1 plant glycosyltransferases,” Phytochemistry; Feb. 2003; vol. 62; pp. 399-413.
Hansen, EH et al, De Novo Biosynthesis of Vanillin in Fission Yeast (Schizosaccharomyces pombe) and Baker's Yeat (Saccharomyces cerevisiae), Applied and Environmental Microbiology; May 13, 2009; vol. 75, No. 9; pp. 2765-2774.
Nature Reviews, “In Brief: Industrial Microbiology,” Nature Reviews Microbiology Report; May 2009; vol. 7, No. 5; p. 324.
Ehrenberg, R., “Yeast Bred to Bear Artificial Vanilla: Scientists co-opt fungi to produce flavor more efficiently,” ScienceNews; May 23, 2009; vol. 176, No. 11.
Ehrenberg, R., “Yeast Bred to Bear Artificial Vanilla: Researchers have co-opted fungi to produce the flavor more efficiently,” ScienceNews; http://www.sciencenews.org/view/generic/id/43124; May 23, 2009; vol. 176, No. 11.
Andersen Thomas Hvid
Hansen Joergen
Okkels Finn Thyge
Berenbaum Weinshienk PC
BLMaps
Joike Michele K
Kalan Kristina M.
Scull Peter B.
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