Method of producing a factor-VIII(AHF)-high-concentrate

Details Method of producing a factor-VIII(AHF)-high-concentrate Method of producing a factor-VIII(AHF)-high-concentrate

1981-07-29

1983-09-13

Bleutge, John C.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424101, 424177, C07G 700

Patent

active

044041314

ABSTRACT:
In a method of producing a factor-VIII(AHF)-high-concentrate having a specific activity of at least 2.5 units AHF and a fibrinogen content of less than 0.25 mg/mg protein from human or animal plasma, the plasma is subjected to a multi-step fractionation. The fraction purified by these fractionation measures and enriched in factor VIII (AHF) is subjected to a cryoalcohol precipitation and the resulting precipitate is processed into a stable form.

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