Method of producing a cationic liposomal preparation...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C514S449000

Reexamination Certificate

active

08075913

ABSTRACT:
A method for producing a cationic liposomal preparation comprising a lipophilic active compound with physical and chemical stability during manufacturing, storing and reconstituting, and further a cationic liposomal preparation obtainable by this method as well as specific cationic liposomal preparations as well as pharmaceutical compositions are disclosed.

REFERENCES:
patent: 5415869 (1995-05-01), Straubinger et al.
patent: 5424073 (1995-06-01), Rahman
patent: 5549910 (1996-08-01), Szoka
patent: 5578320 (1996-11-01), Janoff
patent: 5648090 (1997-07-01), Rahman
patent: 5653998 (1997-08-01), Hamann
patent: 5683715 (1997-11-01), Boni
patent: 5733888 (1998-03-01), Carver
patent: 5821263 (1998-10-01), Scola et al.
patent: 5869680 (1999-02-01), Mas et al.
patent: 6034072 (2000-03-01), Bruno et al.
patent: 6090955 (2000-07-01), Reszka et al.
patent: 6120798 (2000-09-01), Allen et al.
patent: 6140359 (2000-10-01), Carver et al.
patent: 6306894 (2001-10-01), Carver et al.
patent: 7112338 (2006-09-01), McDonald et al.
patent: 2002/0034537 (2002-03-01), Michaelis et al.
patent: 2002/0090392 (2002-07-01), Campbell et al.
patent: 2003/0187062 (2003-10-01), Zenoni et al.
patent: 2011/0159052 (2011-06-01), Deluca et al.
patent: 1 059 092 (2005-07-01), None
patent: 6-211645 (1993-01-01), None
patent: 99/18113 (1997-10-01), None
patent: 98/22451 (1997-11-01), None
patent: 98/28288 (1997-12-01), None
patent: 99/09021 (1998-08-01), None
patent: 98/40052 (1998-09-01), None
patent: 99/14209 (1998-09-01), None
patent: 98/51278 (1998-11-01), None
patent: 98/58630 (1998-12-01), None
patent: 99/65465 (1999-12-01), None
patent: 00/61543 (2000-10-01), None
patent: 01/05374 (2001-01-01), None
patent: 01/10412 (2001-02-01), None
patent: 01/17508 (2001-03-01), None
patent: 01/25223 (2001-04-01), None
patent: 01/56548 (2001-08-01), None
patent: 01/82899 (2001-11-01), None
patent: 01/93836 (2001-12-01), None
Campbell et al (J Pharm Sci. Aug. 8, 2001; 90(8):1091-1105).
Straubinger et al. (Methods in Enzymology: Taxane-Containing Liposomes. 2005; 391: 97-117).
Regueiro-Ren, et al., SAR and pH Stability of Cyano-Substituted Epothilones, Org. Lett., 2002, 4:3815-3818.
Lee, et al., BMS-247550: A novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy, Clin. Cancer Res., 2001, 7:1429-1437.
Grit, et al., Chemical stability of liposomes: implications for their physical stability, Chemistry and Physics of Lipids, 1993, 64:3-18.
Nicolaou, et al., Recent developments in the chemistry, biology and medicine of the epothilones, Chem. Comm., 2001, 1523-1535.
Altmann, et al., Epothilones and related structures, Biochim. Et Biophys. Acta, 2000, 1470:M79-M91.
Seftow, et al., Derivatization of the C12-C13 functional groups of epothilones A, B and C, Bioorg. & Medicinal Chem. Lett., 1998, 8:3031-3036.
Zuidam, et al., Chemical Hydrolysis of Phospholipids, Journal of Pharmaceutical Sciences, 1995, 84:1113-1119.
Stachel, et al., On the total synthesis and preliminary biological evaluations of 15(R) and 15(S) Aza-dEpoB, Org. Lett., 2000, 2:1637-1639.
Sharma, et al., Novel Taxol Formulations: Preparation and Characterization of Taxol-Containing Liposomes, Pharmaceutical Research, 1994, 11(6):889-896.
Sharma, et al., Antitumor effect of taxol-containing liposomes in a taxol-resistant murine tumor model, Cancer Res, 1993, 53:5877-81.
Sharma, et al., Activity of Paclitaxel Liposome Formulations Against Human Ovarian Tumor Xenografts, Int. J. Cancer, 1997, 71:103-107.
Chou, et al., The synthesis, discovery and development of a highly promising class of microtubule stabilization agents, PNAS, 2001, 98:8113-8118.
Thurston, et al., Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice, J Clin. Invest, 1998, 101(7):1401-13.
Vernooij, et al., Chemical hydrolysis of DOTAP and DOPE in a liposomal environment, Journal of Controlled Release, 2002, 79(1-3):299-303.
Crosasso, et al., Preparation, characterization and properties of sterically stabilized paclitaxel-containing liposomes, Journal of Controlled Release, 2000, 63:19-30.
Dordunoo, et al., Solubility and Stability of Taxol: effects of buffers and cyclodextrins, International Journal of Pharmaceutics, 1996, 133: 191-201.
Banerjee, J Biomater Appl. 2001, 16(1): 3-21.
Campbell, et al., Influence of cationic lipids on the stability and membrane properties of paclitaxel-containing liposomes, J Pharm Sci, 2001, 90(8): 1091-1105.
Ceruti, et al., Preparation, characterization, cytotoxicity and pharmacokinetics of liposomes containing water-soluble prodrugs of paclitaxel, Journal of Controlled Release, 2000, 63(1-2): 141-153.
Encyclopedia of Surface and Colloid Science, vol. 1: A-Dif, edited by A. T. Hubbard (2002).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of producing a cationic liposomal preparation... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of producing a cationic liposomal preparation..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of producing a cationic liposomal preparation... will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-4262928

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.