Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide a

Details Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide a Method of producing a bis(2-carboxyethyl)alkyl phosphine oxide a

1996-01-17

1997-10-21

Mosley, Terressa

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

558385, 568 14, 987110, 987125, 987134, C07C 5500

Patent

active

056798490

ABSTRACT:
A method of producing a bis(2-carboxyethyl)-alkyl phosphine oxide represented by the following general formula (1) is disclosed. ##STR1## The method comprises the following Steps 1-4: step 1 wherein phosphine is reacted with acrylonitrile to produce bis(2-cyanoethyl)phosphine and then, in step 2, reacted with an alkene to produce a bis(2-cyanoethyl)alkyl phosphine, and in step 3, reacted with an oxidizing agent to produce a bis(2-cyanoethyl)alkyl phosphine oxide, and in step 4, said bis(2-cyanoethyl)alkyl phosphine oxide is reacted with water or a lower alcohol to give a bis(2-carboxyethyl)alkyl phosphine oxide or a derivative thereof.

REFERENCES:
patent: 4149014 (1979-04-01), Wilson
patent: 4537993 (1985-08-01), Savides et al.

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