Method of producing 3-O-demethylfortimicin B,4-N-alkylfortimicin

Details Method of producing 3-O-demethylfortimicin B,4-N-alkylfortimicin Method of producing 3-O-demethylfortimicin B,4-N-alkylfortimicin

1979-03-29

1980-09-02

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

424180, 536 18, A61K 7131, C07H 1522

Patent

active

042207568

ABSTRACT:
An improved method of 3-O-demethylating fortimicin B or a 4-N-alkylfortimicin B derivative comprising the steps of reacting fortimicin B with lithium in the presence of ethylenediamine and thereafter isolating 3-O-demethylfortimicin B from the reaction mixture.

REFERENCES:
patent: 4124756 (1978-11-01), Martin et al.

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