Method of producing (+) 2-azabicyclo{2.2.1}hept-5-en-3-one

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D20952

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058471570

ABSTRACT:
The present invention relates to a simplified method of producing sulfocyanides by reacting cyclopentadiene with sulfonylcyanides without the use of organic solvents.

REFERENCES:
patent: 5300649 (1994-04-01), Griffiths et al.
Katagiri et al., Hetero Diels-Alder Reaction of Benzenesulfonyl Cyanide with Cyclopentadiene Using Chiral Lewis Acids, Chem. Pharm. Bull. vol. 44, No. 4, (1996) pp. 850-852.
Griffiths et al., Diels-Alder Reaction of Methanesulfonyl Cyanide with Cyclopentadiene. Industrial Synthesis of pp. 6129-6131.
Daluge et al., Synthesis of Carbocyclic Aminonucleosides, J. Org. Chem. vol. 43, No. 12 (1978) pp. 2311-2320.
Jagt et al., Diels-Alder Cycloadditions of Sulfonyl Cyanides with Chem. vol. 39, No. 4 (1974) pp. 564-566. Cyclocondensation of Cyclopentadiene with Phenylsulfonyl Cyanide, Chemical Abstracts, vol. 124, No. 23, (Jun. 3, 1996) Abstract No. 316997a. Abstracts, vol. 121, No. 9 (Aug. 29, 1994) Abstract No. 108525f. Abstracts, vol. 121, No. 9 (Aug. 29, 1994) Abstract No. 108526g.

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