Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Reexamination Certificate
2006-07-18
2006-07-18
Richter, Johann (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
C562S013000
Reexamination Certificate
active
07078393
ABSTRACT:
In a method for preparing 1-hydroxy-1,1-diphosphonic acid compounds of the general formula I and/or of their pharmacologically compatible saltsa compound of the formula IIis reacted with a compound P(OSiR53)3-pR6pand the reaction product is hydrolyzed.
REFERENCES:
patent: 4608368 (1986-08-01), Blum et al.
Marc Lecouvey et al., A mild and efficient one-pot synthesis of 1-hydroxymethylene-1,1-bisphosphonic acids. Preparation of new tripod ligands, “Tetrahedron Letters 42 pp. 8475-8478, 2001”.
Blum Helmut
Greb Wolfgang
Pustovit Yurii
Röschenthaler Gerd-Volker
EUCRO European Contract Research GmbH & Co. KG
Huckett Gudrun E.
Richter Johann
Sackey Ebenezer
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