Method of preventing withdrawal symptoms associated with the ces

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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A61K 31415

Patent

active

045887390

ABSTRACT:
In human subjects accustomed to smoking tobacco the withdrawal symptoms associated with the cessation or reduction of tobacco smoking may be prevented by administering to the subject an effective amount of an alpha-2 adrenergic agonist such as clonidine hydrochloride for a suitable period of time.
Alternatively, such withdrawal symptoms may be prevented by administering to such a person an effective amount of alprazolam.

REFERENCES:
patent: 4255439 (1981-03-01), Cooper
patent: 4382946 (1983-05-01), Sjoendsma
Internal Medicine Alert 6:85 (1984).
Glassman, A. H. et al.: Science 226: 864-866 (1984).
Modern Drug Encyl. & Therapeutic Index, 14th (1977), pp. 193-195.
Chem. Abst. vol. 97, Chem. Subj. Index, CH.fwdarw.IO (1982), 3314cs.

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