Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1980-07-29
1982-11-02
Hazel, Blondel
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3702, C07C10352
Patent
active
043573223
ABSTRACT:
Inflammation is prevented, reduced or inhibited by administering muramyl and desmethylmuramyl dipeptides of the general formula: ##STR1## wherein each of R.sup.1 through R.sup.5 can independently be hydrogen or a variety of substituted or unsubstituted acyl, alkyl, aryl, or arylalkyl substituents. Pharmaceutical compositions containing such compounds useful for reducing inflammation are described.
REFERENCES:
patent: 4082735 (1978-04-01), Jones et al.
patent: 4082736 (1978-04-01), Jones et al.
patent: 4101649 (1978-07-01), Adam et al.
Chedid et al., Proc. Natl. Acad. Sci., U.S.A., vol. 74, pp. 2089-2093, 1977.
Ackerman Neil R.
Rooks, II Wendell H.
Tomolonis Albert J.
Hazel Blondel
Kanagy James M.
Krubiner Alan M.
Moran Tom M.
Syntex (U.S.A.) Inc.
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