Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof
Patent
1994-12-21
1997-10-07
Feisee, Lila
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Monoclonal antibody or fragment thereof
4241431, 4241531, 4241541, 4241551, 4241721, 4241731, 4241741, 514 2, 514 8, A61K 39395, A61K 3512, A61K 3802
Patent
active
056744927
ABSTRACT:
There is disclosed a method of treating a mammal afflicted with a disease characterized by neoplastic cells that express CD40, comprising administering a therapeutically effective amount of a CD40 binding protein in a pharmaceutically acceptable buffer. CD40 binding proteins include monoclonal antibodies to CD40, and CD40 ligand. CD40 binding proteins may also be used to prevent disease characterized by neoplastic cells that express CD40, in individuals at risk for such disease.
REFERENCES:
Heath et al. Cell Immunol. 152: 468-480 (1993).
Warner et al Cell Immunol. 115: 195-203 (1988).
Law Leukemia 4: 732-738 (1990).
Dermer Biotechnology 12: 320 (1994).
Dillman J Clin Oncol. 12: 1497-1535 (1994).
Ferraiolo Plenum Press NY 1992.
Armitage Richard J.
Fanslow, III William C.
Longo Dan L.
Murphy William J.
Feisee Lila
Gambel Phillip
Immunex Corporation
Perkins Patricia Anne
The United States of America as represented by the Department of
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