Drug – bio-affecting and body treating compositions – Dentifrices
Patent
1995-04-13
1996-12-24
Seidleck, James J.
Drug, bio-affecting and body treating compositions
Dentifrices
424 54, 528328, 528363, A61K 716, A61K 722
Patent
active
055871461
ABSTRACT:
Copolymers of polyaspartic acid which are suitable for the inhibition of scale deposition were obtained by reacting maleic acid, an additional polycarboxylic acid and ammonia in a stoichiometric excess, at 120.degree.-350.degree. C., preferably 180.degree.-300.degree. C., to provide copolymers of polysuccinimide. In a second embodiment, a polyamine was added to the reaction mix. These intermediate polysuccinimide copolymers could then be converted to the salts of copolymers of polyaspartic acid by hydrolysis with a hydroxide.
Such copolymers are useful in preventing deposition of scale from water and find applications in treating water. Other applications include scale prevention additives for detergents. In addition, such copolymers inhibit dental tartar and plaque formation.
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Calton Gary J.
Wood Louis L.
Bayer AG
Hampton-Hightower P.
Seidleck James J.
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