Method of preventing dental caries and other oral lesions

Drug – bio-affecting and body treating compositions – Dentifrices

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424 50, 424 58, 4241951, A61K 716, A61K 726, A61K 3578

Patent

active

059723114

ABSTRACT:
The present invention relates to a method of preventing caries and other sugar-dependent dental and oral lesions and to a carbohydrate binding protein-based composition suitable for use therein.

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Overvoorde et al, "A Plasma Membrane Sucrose-binding Protein That Mediates Sucrose Uptake Shares Structural and Sequence Similarity with Seed Storage Proteins but Remains Functionally Distinct", The Journal of Biological Chemistry 272(25):15898-15904 (1997).
Careaga et al, "Large Amplitude Twisting Motions of an Interdomain Hinge: A Disulfide Trapping Study of the Galactose-Glucose Binding Protein", Biochemistry 34:3048-3055 (1995).
Overvoorde and Grimes, "Topographical Analysis of the Plasma Membrane-associated Sucrose Binding Protein from Soybean", The Journal of Biological Chemistry 269(21):15154-15161 (1994).
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