Method of preventing and treating obesity

Details Method of preventing and treating obesity Method of preventing and treating obesity

1984-10-10

1987-09-29

Brown, J. R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 552, A61K 3170

Patent

active

046969195

ABSTRACT:
A method of diminishing appetite, in turn preventing and treating obesity, by administration of a compound of the formula ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and selected from a hydrogen atom or an acetyl group, or its pharmaceutically acceptable acid addition salt, and a pharmaceutical composition containing as an active ingredient the compound represented by the above formula.

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Mommsen, "Chitinase and .beta.-N-Acetylglucosaminidase from the Digestive Fluid of the Spider, Cupiennius salei", Chem. Abstr. 92:193322n, vol. 92, No. 23, Jun. 9, 1980, p. 245.
Grajeswar et al, "Synthesis and Biological Activity of Some 1-N-Substituted Acetamido-2-Deoxy-.beta.-D-Glycopyranosylamine Derivatives and Related Analogs" Carbohydrate Research, 80 (1980) 99-115, Elsevier Scientific Publishing Co.
Ng Ying Kin et al, "The Deamination of Pyranose Amines, Part I, Equatorial Aines", J. Chem. Soc(C), 1971, pp. 1578-1583.
T. Sakata et al., Feeding and Hyperglycemia Induced by 1,5-Anhydroglucitol in the Rat (Physiol. Behav., 27: 401-405, 1981).
K. Tsutsui et al., Feeding Suppression Induced by Intra-Ventricle III Infusion of 1,5-Anhydroglucitol (Physiol. Behav. 31; 493-502, 1983).

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