Method of preventing and treating cerebral insufficiency

Details Method of preventing and treating cerebral insufficiency Method of preventing and treating cerebral insufficiency

1982-04-09

1983-10-11

Friedman, Stanley J.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

A61K 3133

Patent

active

044092121

ABSTRACT:
The invention relates to a method of preventing or treating cerebral insufficiency, which method comprises administering to a human being in need of such treatment, orally or rectally, a prophylactic or a therapeutically effective amount of a compound of the general formula I ##STR1## wherein X.sub.1 is hydrogen, halogen having an atomic number up to 35, or is cyano, and X.sub.2 and Y together are an additional bond, or X.sub.1 and X.sub.2 together are the oxo radical and Y is hydrogen, or X.sub.1 is hydroxy and X.sub.2 and Y are hydrogen. Examples of suitable compounds are 10,11-dihyro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide, 10,11-dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide and, in particular, carbamazepine (5H-dibenz[b,f]azepine-5-carboxamide).

REFERENCES:
patent: 3637662 (1972-01-01), Razdan
patent: 4076812 (1978-02-01), Allgeier et al.
B. M. Kulig and H. Meinardi, Adv. Epileptol, Proc. Congr. Int. League Epilepsy; 13th, 1977 pp. 89-103, C.A. 90, 115155e.
George M. Jacobides, Adv. Epileptol, Proc. Congr. Int. League Epilepsy, 13th, 1977 pp. 114-119, CA 90 11539n.
S. J. Sara and D. Lefevre, Psychopharmacologia 25, 32-40, (1972).
William O. Boggan and Kurt Sclesinger, Behavioral Biology, 12, 127-134, (1974).

Affiliated with

Also associated with

Rating

Method of preventing and treating cerebral insufficiency does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preventing and treating cerebral insufficiency, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preventing and treating cerebral insufficiency will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1274979