Method of preserving tissue

Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or... – Including freezing; composition therefor

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C435S001100, C435S325000, C435S374000

Reexamination Certificate

active

07129035

ABSTRACT:
This invention relates to the sterilization and preservation of tissue for storage. More specifically, the invention relates to a method of using a solution to form a preserved tissue. The solution includes a radical scavenger at a concentration believed to reduce the damage to the tissue that could otherwise occur during sterilization with ionizing radiation.

REFERENCES:
patent: 2832689 (1958-04-01), Proctor et al.
patent: 3808113 (1974-04-01), Okamura et al.
patent: 4155331 (1979-05-01), Lawrence et al.
patent: 4179338 (1979-12-01), Gordon
patent: 4456589 (1984-06-01), Holman et al.
patent: 4620908 (1986-11-01), Van Duzer
patent: 4798611 (1989-01-01), Freeman, Jr.
patent: 4890457 (1990-01-01), McNally et al.
patent: 5012503 (1991-04-01), Nambu et al.
patent: 5071741 (1991-12-01), Brockbank
patent: 5096553 (1992-03-01), Ross et al.
patent: 5110722 (1992-05-01), Brockbank et al.
patent: 5122110 (1992-06-01), McNally et al.
patent: 5131850 (1992-07-01), Brockbank
patent: 5145769 (1992-09-01), McNally et al.
patent: 5257692 (1993-11-01), Heacox
patent: 5279964 (1994-01-01), Chrisope
patent: 5283034 (1994-02-01), Okrongly et al.
patent: 5328821 (1994-07-01), Fisher et al.
patent: 5362442 (1994-11-01), Kent
patent: 5403834 (1995-04-01), Malfroy-Camine et al.
patent: 5485496 (1996-01-01), Lee et al.
patent: 5609866 (1997-03-01), Khan et al.
patent: 5677019 (1997-10-01), Carstairs et al.
patent: 5730933 (1998-03-01), Peterson
patent: 5989498 (1999-11-01), Odland
patent: 6140123 (2000-10-01), Demetriou et al.
patent: 6171549 (2001-01-01), Kent
patent: 6346216 (2002-02-01), Kent
patent: 6365338 (2002-04-01), Bull et al.
patent: 6908591 (2005-06-01), MacPhee et al.
patent: 2001/0000804 (2001-05-01), Goldstein et al.
patent: WO 93/11666 (1993-06-01), None
patent: WO 96/27287 (1996-09-01), None
patent: WO 99/60849 (1999-12-01), None
patent: WO 02/32225 (2002-04-01), None
patent: WO 03/026704 (2003-04-01), None
patent: WO 03/092745 (2003-11-01), None
Campbell, D.G. et al.,Sterilization of HIV by Gamma Irradiation. A Bone Allograft Model., Int. Orthop, vol. 18: No. 3, pp. 172-176, Jun. 1994.
Cooper, D.E. et al., “Contaminated Patellar Tendon Grafts: Incidence of Positive Cultures and Efficacy of an Antibiotic Solution Soak—an In Vitro Study”, Arthroscopy vol. 7, No. 3, pp. 272-274, 1991.
Dichtelmuller, H. et al., “Validation of Virus Inactivation and Removal for the Manufacturing Procedure of Two Immunoglobulins and a 5% Serum Protein Solution Treated with Beta-Propiolactone”, Biologicals, vol. 21: No. 3, pp. 259-268. Sep. 1993.
Erickson, G.A. et al., “Detection and Elimination of Adventitious Agents in Continuous Cell Lines”, Dev Biol Stand, vol. 70, pp. 59-66, 1989.
Goertzen, M.J. et al., “Anterior Cruciate Ligaments Reconstruction Using Cryopreserved Irradiated Bone-ACL-Bone-Allograft Transplants”, Knee Surg Sports Traumatol Arthors, vol. 4: No. 3, pp. 190, 1996.
Keller, K.M., “Action of Hydrogen Peroxide on Degradation of DNA After Irradiation in Escherichia coli”, Int J Radiat Biol Relat Stud Phys Chem Med, vol. 31: No. 5, pp. 407-413, May 1977.
Lafferty, H.H. et al., “The Analysis of Decay Curves”, Clin Sci Mol Med, vol. 52: No. 1, pp. 97-101, Jan. 1977.
Lee, S.F. et al., “Induction Of c-Jun Protooncogene Expression By Hydrogen Peroxide Through Hydroxyl Radical Generation and p60SRCTyrosine Kinase Activation”, Free Radic Biol. Med. vol. 21, No. 4, pp. 437-448, 1996.
Lindsey, M.E. et al., “Quantitation of Hydroxyl Radical During Fenton Oxidation Following a Single Addition of Iron and Peroxide”, Chemosphere, vol. 41, No. 3, pp. 409-417, Aug. 2000.
Liu, B. et al., “Mouse Antibody Response Following Repetitive Injections of Gamma-Irradiated Human Placenta Collagen”, Chin Med Sci J. (China), vol. 9: No. 2, pp. 100-103, Jun. 1994.
Mello Filho, A.C. et al., “Cell Killing and DNA Damage by Hydrogen Peroxide are Mediated by Intracellular Iron”, Biochem J, vol. 218: No. 1, pp. 273-275, Feb. 1984.
Mulford, D.J. et al., “Glutathione-S-Transferase-Mediated Methylthio Displacement and Turnover in the Metabolism of Pentachlorothioanisole by Rats”, Xenobiotica, vol. 21, No. 5, pp. 597-603, May, 1991.
Patchen, M.L. et al., “Glucan: Mechanisms Involved in its “Radioprotective” Effect”, J. Leukocyte Biol. vol. 42: No. 2, pp. 95-105, Aug. 1987.
Price, C.C. et al., “The Thermal Decomposition of Dimsyl Ion in Dimethyl Sulfoxide”, J. Org Chem, vol. 34: No. 9, pp. 2503-2506, Sep. 1969.
Repine, J.E. et al., “Hydrogen Peroxide Kills Staphylococcus aureus by Reacting with Staphylococcal Iron to Form Hydroxyl Radical”, J Biol Chem, vol. 256: No. 14, pp. 7094-7096, Jul. 1981.
Reszka, K.J. et al.,Free Radical Reactions Photosensitized by the Human Lens Component, Hynurenine: an EPR and Spin Trapping Investigation, Free Radic. Biol. Med. vol. 20, No. 1, pp. 23-24, 1996.
Rimbach, G. et al., “Liver and Colon Oxidant Status in Growing Rats Fed Increasing Levels of Dietary Iron”, J. Trace Elem. Med. Biol. vol. 11, No. 2, pp. 99-104, Jun. 1997.
Schiller, J. et al., “Reactivity of Cartilage and Selected Carbohydrates with Hydroxyl Radicals: an NMR Study to Detect Degradation Products”, Free Radic Res, vol. 28: No. 2, pp. 215-228, Feb. 1998.
Shen, B. et al., “Increased Resistance to Oxidative Stress in Transgenic Plants by Targeting Mannitol Biosynthesis to Chloroplasts”, Plant Physiol., vol. 113, No. 4, pp. 1177-1183, Apr. 1997.
Vasin, M.V., “Radioprotective Efficiency of Indraline With Local Gamma Radiation of the Skin”, Radiats Biol Radioecol (Russian), vol. 38: No. 1, pp. 42-54, Jan.-Feb. 1998.
“Virus Inactivation in Plasma Products”, Current Studies in Hematology and Blood Transfusion, vol. 56, pp. 1-158, no year.
Weiss, H. et al., “Oxygen Depletion in Cells Irradiated at Ultra-High Dose-Rates and at Conventional Dose-Rates”, Int J. Radiat Biol., Relat Stud Phys Chem Med, vol. 26: No. 1, pp. 17-29, Jul. 1974.
Willkommen, H. et al., “Theoretical Considerations on Viral Inactivation or Elimination”, Dev Biol Stand, vol. 81, pp. 109-116, 1993.
Zhang, L. et al., “Effect of a Combined Gamma Irradiation and Parylene Plasma Treatment on the Hydrolytic Degradation of Synthetic Biodegradable Sutures”, J. Biomed Mater Res, vol. 27: No. 11, pp. 1425-1441, Nov. 1993.
Abot, K. et al., “Dimethylsulfoxide Increases the Survival and Lysosomal Stability of Mouse Peritoneal Macrophages Exposed to Low-LET Ionizing Radiation and/or Lioniclron in Culture”, Virchows Arch B Cell Pathol Incl Mol Pathology, vol. 46: No. 4, pp. 307-320, 1984.
Angell, W.W. et al., “Long-Term Follow-Up of Viable Frozen Aortic Homografts A Viable Homograft Valve Bank”, J. Thorac Cardiovasc. Surg. vol. 93: No. 6, pp. 815-822, Jun. 1987.
Antoku, S., “Chemical Protection of Bacteria and Cultured Mammalian Cells by Sulfur-Containing Compounds”, J. Radiat Res (Tokyo), vol. 16: No. 1, pp. 28-36, Mar. 1975.
Antoku, S. et al., “Effect of Oxygen on Bacteria and Cultured Mammalian Cells Irradiated in the Frozen State”, Int'l. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med., vol. 32: No. 2, pp. 145-152, Aug. 1977.
Aparicio, S.R. et al., “Light and Electron Microscopy Studies on Homograft and Heterograft Heart Valves”, J Path, vol. 115, pp. 147-162, 1975.
Arroyo, C.M. et al., “ESR Study of Electron Transfer Reactions Between Gamma-Irradiated Pyrimidines, Adriamycin and Oxygen”, Free Radic Bio Med, vol. 9: No. 3, pp. 191-197, 1990.
Babbs, C.F. et al., “Colorimetric Assay for Methanesulfinic Acid in Biological Samples”, Analytical Biochemistry vol. 163, pp. 67-73, 1987.
Babbs, C.F. et al.,Detection and Quantitation of Hydroxyl Radical Using Dimethyl Sulfoxide as Molecular Probe, Methods in Enzymology, vol. 186, pp. 137-147, 1990.
Babbs, C.F. et al.,Scatch

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Method of preserving tissue does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preserving tissue, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preserving tissue will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3710953

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.