Method of preserving platelets with apyrase and an antioxidant

Details Method of preserving platelets with apyrase and an antioxidant Method of preserving platelets with apyrase and an antioxidant

1992-07-24

1995-01-03

Wityshyn, Michael G.

Chemistry: molecular biology and microbiology

Maintaining blood or sperm in a physiologically active state...

435 1, 435212, 424532, A01N 102, C12N 948

Patent

active

053786017

ABSTRACT:
The invention provides a method and composition for preserving platelets which is based on the use of a composition which includes apyrase and an antioxidant. Preferred compositions will also include a protease inhibitor and optionally a solvent.

REFERENCES:
patent: Re32874 (1989-02-01), Rock
patent: 4059967 (1977-11-01), Rowe
patent: 4396716 (1983-08-01), Marconi
Kinlough-Rathbone, Properties of Washed Platelets, Thrombos. Haemostas 1977 37 pp. 291-308.
Bode Arthur, The Use of Thrombin Inhibitors and Aprotinin Lab & Clinical Med 113 (6) Jun. 1989, pp. 753-758.
Mazoyer E., Platelet Membrane Glycoproteins . . . Throbosis Res 62, 1991, pp. 165-175.
Bode, Arthur, The Use of Inhibitors of Platelet Activation . . . Blood Cells 1992 18: 361-380.

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