Method of preserving corneal tissue using...

Chemistry: molecular biology and microbiology – Differentiated tissue or organ other than blood – per se – or...

Reexamination Certificate

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Reexamination Certificate

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07371513

ABSTRACT:
Tissue preservation media comprising a polyoxyethylene/polyoxypropylene copolymer are used to preserve tissues and organs for storage and transplantation. In particular embodiments, the polyoxyethylene/polyoxypropylene copolymer is Pluronic F68 or FLOCOR (CRL-5861; purified poloxamer 188), and the medium is Steinhardt medium, polyoxyethylene/polyoxypropylene copolymer-supplemented Optisol GS or polyoxyethylene/polyoxypropylene copolymer-supplemented ViaSpan.

REFERENCES:
patent: 7087369 (2006-08-01), Steinhardt
patent: 2007/0087320 (2007-04-01), Licari et al.
patent: 2005-013690 (2005-02-01), None
patent: 2007008697 (2007-01-01), None
Sato et al., “Effects of pulronic F68 on t-PA producing Chinese hamster ovary (CHO) cells under agitating and static conditions”, Animal Cell Technology: Basic & Applied Aspects, Proceedings of the Annual Meeting of the Japanese Association for Animal Cell Technology, 15th, Fuchu, Japan, Nov. 11-15, 2002 (2003): 173-177. Kluwer Academic Publishers.
Solberg et al., A New Protective Solution for Hypothermic Storage of Free Vein Grafts in Cardiovascular Surgery. Scand J Clin Lab Invest 1992, 52 (2), p. 73-82.
Cavallari et al., University of Wisconsin Solution Effects on Intimal Proliferation in Canine Autogenous Vein Grafts, J Surgical Res 1995, 59, p. 433-440.
Andrew et al., Comparison of Optixol and neomycin-Polymyxin B-Gramicidin Opthalmic Solution for Corneal Storage in the Dog. Veterinary Ophthalmol 1999, 2 (3) p. 155-161.

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