Method of preserving arylacylamidase in aqueous solution

Details Method of preserving arylacylamidase in aqueous solution Method of preserving arylacylamidase in aqueous solution

1992-01-21

1993-02-23

Naff, David M.

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Stablizing an enzyme by forming a mixture, an adduct or a...

435227, 435187, C12N 996, C12N 978

Patent

active

051889552

ABSTRACT:
Arylacylamidase can be stabilized by inhibiting conformational changes using either o-cresol or benzoic acid or salts of benzoic acid as a stabilizing agent. The compositions show significantly enhanced stability of arylacylamidase in aqueous solution, lyophilized, and solid-phase formats.

REFERENCES:
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patent: 4414327 (1983-11-01), Hammond et al.
patent: 4430433 (1984-02-01), Hammond et al.
patent: 4675296 (1987-06-01), Lehmussaari et al.
patent: 4764468 (1988-08-01), Wehner et al.
patent: 4999288 (1991-03-01), de Castro et al.

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