Method of preparing tissue thromboplastin

Details Method of preparing tissue thromboplastin Method of preparing tissue thromboplastin

1982-12-01

1983-11-22

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112B, 424 95, 424101, 424105, 435 13, 435212, C07G 700, C07G 7026

Patent

active

044168128

ABSTRACT:
A tissue thromboplastin preparation which is sensitive to coagulation factor VII, is prepared from acetone dry powder mammalian tissue, by extraction with a salt solution containing 1 to 20 mmol/1 of calcium ions and, if desired, a surface active agent, after which the extract maybe dried.

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patent: 3228841 (1966-01-01), Cohen et al.
patent: 3522148 (1970-07-01), Adam et al.
patent: 3980432 (1976-09-01), Trobisch et al.
patent: 3983004 (1976-09-01), Trobisch et al.
Thrombosis Hemostasis, 1939, 592-599, (1978), Stuttgart.
Biochem. Soc. Trans. 8, 133, (1980), Gardiner et al.
`Human Blood Coagulation, Hemostasis and Thrombosis`, (R. Biggs Editor, Oxford), 1976, p. 663.

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