Method of preparing therapeutic amides

Details Method of preparing therapeutic amides Method of preparing therapeutic amides

1996-08-23

1997-11-04

Raymond, Richard L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

544318, 544333, 544335, 544408, 546223, 546262, 546275, 546280, 546283, 546284, 546292, 546294, 546309, 546316, 548187, 548200, 548213, 548214, 548228, 548229, 548232, 548236, 548243, 549 66, 549 72, 549475, 549487, 558 44, 560107, 560255, 564123, 564189, 564190, C07C23516, C07D21338, C07D21375

Patent

active

056841981

ABSTRACT:
Amides having formula I: ##STR1## wherein E, X, R.sup.2 and R.sup.3 have the meanings given in the specification, and pharmaceutically acceptable salts and pharmaceutically acceptable in vivo hydrolysable esters thereof,
which are useful in the treatment of urinary incontinence. Further provided are processes for preparing the aides and pharmaceutical compositions containing them.

REFERENCES:
patent: 3365485 (1968-01-01), Bell
patent: 3468878 (1969-09-01), Bell
patent: 3715375 (1973-02-01), Shen et al.
patent: 4191775 (1980-03-01), Glen
patent: 4239776 (1980-12-01), Glen
patent: 4282218 (1981-08-01), Glen et al.
patent: 4294851 (1981-10-01), Metz et al.
patent: 4386080 (1983-05-01), Crossley et al.
patent: 4535092 (1985-08-01), Hughes
patent: 4636505 (1987-01-01), Tucker
patent: 4880839 (1989-11-01), Tucker
patent: 5032592 (1991-07-01), Hughes et al.
patent: 5272982 (1993-12-01), Russell et al.
R Bayles et al., "The Smiles rearrangement of 2-aryloxy-2-methylpropanamides. Synthesis of N-aryl-2-hydroxy-2-methylpropanamides" Synthesis. (1977), 31-33.
G Edwards et al., "Structure-activity relationships of potassium channel openers", Trends in Pharmacological Sciences. (1990), 11, 417-422.

Affiliated with

Also associated with

Rating

Method of preparing therapeutic amides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preparing therapeutic amides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing therapeutic amides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1834416