Method of preparing sustained-release pharmaceutical/preparation

Details Method of preparing sustained-release pharmaceutical/preparation Method of preparing sustained-release pharmaceutical/preparation

1986-11-10

1989-08-01

Silverberg, Sam

Coating processes

Fraud or tamper detecting

424468, A61K 922

Patent

active

048532495

ABSTRACT:
A method of preparing a sustained-release pharmaceutical preparation, which comprises applying a solution of a binder in water or an alcohol and a fine powder of a hydrophobic solid material which does not easily dissolve within the stomach and intestines to the surface of solid particles containing a drug while the solid particles are being tumbled, thereby to coat the solid particles with the binder and the hydrophobic solid material.

REFERENCES:
patent: 2921883 (1960-01-01), Reese
patent: 3115441 (1963-12-01), Hermelin
patent: 4568560 (1986-02-01), Schobel
patent: 4572833 (1986-02-01), Pedersen
patent: 4684516 (1987-08-01), Bhutani

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