Method of preparing polypeptide binding compositions derived fro

Details Method of preparing polypeptide binding compositions derived fro Method of preparing polypeptide binding compositions derived fro

1995-06-05

1998-12-22

Guzo, David

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

4351723, C12P 2100, C12P 2108, C12N 1513

Patent

active

058518010

ABSTRACT:
Proteinaceous binding compositions are prepared employing hybrid DNA technology, where the variable region polypeptides of immunoglobulins are substantially reproduced to provide relatively small protein molecules having binding specificity and lacking the undesirable aspects of the heavy regions of immunoglobulins. The compositions find a wide range of use, particularly for physiological purposes for diagnosis and therapy. The binding compositions may be modified by labeling with radioisotopes, fluorescers, and toxins for specific applications in diagnosis or therapy.

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