Method of preparing mycophenolic acid glucoside

Details Method of preparing mycophenolic acid glucoside Method of preparing mycophenolic acid glucoside

1979-12-11

1980-11-18

Tanenholtz, Alvin E.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435892, 435 78, C12P 1960

Patent

active

042346843

ABSTRACT:
An improved method of preparing mycophenolic acid glucoside which comprises contacting mycophenolic acid with glucose in an aqueous medium in the presence of a glucosylating enzyme selected from that produced by Streptomyces candidus NRRL 5449 and that produced by Streptomyces aureofaciens NRRL 2209 until mycophenolic acid glucoside is formed.

REFERENCES:
patent: 3184887 (1965-05-01), Winter
patent: 3932619 (1976-01-01), Brannon et al.
Kieslich, Microbial Transformation of Non-Steroid Cyclic Compounds, pp. 154-158, (1976).

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