Method of preparing liposomes and products produced thereby

Details Method of preparing liposomes and products produced thereby Method of preparing liposomes and products produced thereby

1986-03-21

1988-05-17

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 4, 424 5, 424450, 424491, 424493, 514 3, 514 31, A61K 916, A61K 3722, A61K 950

Patent

active

047449896

ABSTRACT:
A method is provided for preparing stable liposome precursors in the form of a water-soluble carrier material coated with a predetermined amount of a thin film of liposome components, which method includes the steps of dissolving at least one liposome-forming amphipathic lipid, optionally, at least one biologically active compound, and, optionally, at least one adjuvant in a suitable organic solvent and employing the resulting organic solution to coat a suitable water-soluble carrier material to form thin film of predetermined amount of liposome components thereon. Upon exposing the coated carrier material to water, the thin films of liposome components hydrate and the carrier material dissolves to give liposome preparations.

REFERENCES:
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4229360 (1980-10-01), Schneider et al.
patent: 4247411 (1981-01-01), Vanlerberghe et al.
patent: 4311712 (1982-01-01), Evans et al.
patent: 4508703 (1985-04-01), Redziniak et al.
Ryman, B. E., "The Use of Liposomes as Carriers of Drugs and Other Cell-Modifying Molecules," Proc. 6th Int'l. Congr. Pharmacol. 5, 91 (1976).

Affiliated with

Also associated with

Rating

Method of preparing liposomes and products produced thereby does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Method of preparing liposomes and products produced thereby, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing liposomes and products produced thereby will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1880632