Method of preparing inhibitors phosphodiesterase-4

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C546S122000

Reexamination Certificate

active

10530465

ABSTRACT:
In one aspect, the present invention is directed to a one pot method of preparing intermediates of Formula (V), which are useful in making inhibitors of phosphodiesterase-4: The present invention is also directed to a method of preparing phosphodiesterase inhibitors comprising the Formula (IX, IXa).

REFERENCES:
patent: 4220646 (1980-09-01), Cotrel et al.
patent: 6677351 (2004-01-01), Li et al.
patent: 6743802 (2004-06-01), Guay et al.
patent: 20 50 111 (1975-11-01), None
J. Org. Chem., vol. 64, No. 16, pp. 6102-6105, 1999.
J. Org. Chem., vol. 64, pp. 6102-6105, 1999.
Journal of the American Chemical Society, vol. 121, No. 41, pp. 9550-9561, 1999.

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