Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form
Reexamination Certificate
2006-05-08
2008-12-23
Kishore, Gollamudi (Department: 1612)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
C514S832000, C514S937000, C424S450000
Reexamination Certificate
active
07468191
ABSTRACT:
The present invention provides a method of making a FC emulsion. The method comprises mixing an FC immiscible hydrophilic liquid and a solid emulsifying agent by agitation at a temperature elevated above the phase transition temperature of the emulsifying agent and below the boiling temperature of the FC immiscible hydrophilic liquid, and adding FC to the mixture of step (a) and agitating at the elevated temperature to disperse droplets of FC in the FC immiscible hydrophilic liquid to form the FC emulsion. The invention also provides another method of making an FC emulsion, which does not require a solid emulsifying agent. The method comprises mixing an FC immiscible hydrophilic liquid and an emulsifying agent to form a first mixture; mixing a stabilizing agent with the first mixture to form a second mixture; and mixing FC with the second mixture to form a third mixture to disperse droplets of FC in the FC immiscible hydrophilic liquid and to form the FC emulsion, wherein the stabilizing agent reduces ability of the droplets to move within a continuous phase of the FC emulsion.
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Creech Jeffrey L.
Hsu Li-Chien
Kivinski Margaret A.
Zalesky Paul J.
Kishore Gollamudi
Kivinski, PE, Esq. Margaret A.
TherOx, Inc.
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