Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes
Patent
1993-11-30
1996-12-17
Kishore, Gollamudi S.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Liposomes
424 951, 264 41, 264 43, A61K 9127
Patent
active
055851126
ABSTRACT:
Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful, for example, in ultrasonic imaging applications and in therapeutic drug delivery systems.
REFERENCES:
patent: 3532500 (1970-10-01), Priest et al.
patent: 3873564 (1975-03-01), Schneider et al.
patent: 4089801 (1978-05-01), Schneider
patent: 4162282 (1979-07-01), Fulwyler et al.
patent: 4192859 (1980-03-01), Mackaness et al.
patent: 4224179 (1980-09-01), Schneider
patent: 4229360 (1980-10-01), Schneider et al.
patent: 4276885 (1981-07-01), Tickner et al.
patent: 4310505 (1982-01-01), Baldeschwieler et al.
patent: 4310506 (1982-01-01), Baldeschwieler
patent: 4315514 (1982-02-01), Drewes et al.
patent: 4331654 (1982-05-01), Morris
patent: 4344929 (1982-08-01), Bonsen et al.
patent: 4426330 (1984-01-01), Sears
patent: 4428924 (1984-01-01), Millington
patent: 4442843 (1984-04-01), Rasor et al.
patent: 4466442 (1984-08-01), Hilmann et al.
patent: 4533254 (1985-08-01), Cook et al.
patent: 4534899 (1985-08-01), Sears
patent: 4544545 (1985-10-01), Ryan
patent: 4569836 (1986-02-01), Gordon
patent: 4572203 (1986-02-01), Feinstein
patent: 4586512 (1985-05-01), Do-huu et al.
patent: 4603044 (1986-07-01), Geho et al.
patent: 4615879 (1986-10-01), Runge et al.
patent: 4620546 (1986-11-01), Aida et al.
patent: 4646756 (1987-03-01), Watmough et al.
patent: 4657756 (1987-04-01), Rasor et al.
patent: 4658828 (1987-04-01), Dory
patent: 4675310 (1987-06-01), Chapman et al.
patent: 4681119 (1987-07-01), Rasor et al.
patent: 4684479 (1987-08-01), D'Arrigo
patent: 4689986 (1987-09-01), Carson et al.
patent: 4718433 (1988-01-01), Feinstein
patent: 4728575 (1988-03-01), Gamble et al.
patent: 4728578 (1988-03-01), Higgins et al.
patent: 4731239 (1988-03-01), Gordon
patent: 4737323 (1988-04-01), Martin et al.
patent: 4774958 (1988-10-01), Feinstein
patent: 4775522 (1988-10-01), Clark, Jr.
patent: 4776991 (1988-10-01), Farmer et al.
patent: 4781871 (1988-11-01), West, III et al.
patent: 4790891 (1988-12-01), Halliday et al.
patent: 4830858 (1989-05-01), Payne et al.
patent: 4844882 (1989-07-01), Widder
patent: 4863717 (1989-09-01), Keana
patent: 4865836 (1989-09-01), Long, Jr.
patent: 4877561 (1989-10-01), Iga et al.
patent: 4893624 (1990-01-01), Lele
patent: 4895719 (1990-01-01), Radhakrishnan et al.
patent: 4898734 (1990-02-01), Mathiowitz et al.
patent: 4900540 (1990-02-01), Ryan
patent: 4921706 (1990-05-01), Roberts et al.
patent: 4927623 (1990-05-01), Long, Jr.
patent: 4938947 (1990-07-01), Nicolau et al.
patent: 4957656 (1990-09-01), Cerny et al.
patent: 4981692 (1992-01-01), Popescu et al.
patent: 4987154 (1991-01-01), Long, Jr.
patent: 4996041 (1991-02-01), Arai et al.
patent: 5000960 (1991-03-01), Wallach
patent: 5008050 (1991-04-01), Cullis et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5045304 (1991-09-01), Schneider et al.
patent: 5049388 (1991-09-01), Knight et al.
patent: 5088499 (1992-02-01), Unger
patent: 5123414 (1992-06-01), Unger
patent: 5137928 (1992-08-01), Erbel et al.
patent: 5141738 (1992-08-01), Rasor et al.
patent: 5144703 (1992-05-01), Wolf et al.
patent: 5147631 (1992-09-01), Glajch et al.
patent: 5149319 (1992-09-01), Unger
patent: 5171755 (1992-12-01), Kaufman
patent: 5186922 (1993-02-01), Shell et al.
patent: 5190982 (1993-03-01), Erbel et al.
patent: 5194266 (1993-03-01), Abra et al.
patent: 5195520 (1993-03-01), Schlief et al.
patent: 5196183 (1993-03-01), Yudelson et al.
patent: 5198225 (1993-03-01), Meybeck et al.
patent: 5205287 (1993-04-01), Erbel et al.
patent: 5209720 (1993-05-01), Unger
patent: 5213804 (1993-05-01), Martin et al.
patent: 5215680 (1993-06-01), D'Arrigo
patent: 5219538 (1993-06-01), Henderson
patent: 5228446 (1993-07-01), Unger et al.
patent: 5230882 (1993-07-01), Unger
patent: 5271928 (1993-12-01), Schneider
patent: 5288446 (1993-07-01), Unger
patent: 5305757 (1994-04-01), Unger et al.
patent: 5310540 (1994-05-01), Giddey et al.
patent: 5316771 (1994-05-01), Barenholtz et al.
patent: 5334381 (1994-08-01), Unger
patent: 5350571 (1994-09-01), Kaufmann et al.
patent: 5352435 (1994-10-01), Unger
patent: 5380519 (1995-01-01), Schneider et al.
patent: 5393524 (1995-02-01), Quay
patent: 5409688 (1995-04-01), Quay
patent: 5410516 (1995-04-01), Uhlendorf et al.
patent: 5413774 (1995-05-01), Schneider et al.
patent: 5425366 (1995-06-01), Reinhardt et al.
patent: 5433204 (1995-07-01), Olson
patent: 5445813 (1995-08-01), Schneider et al.
patent: B14229360 (1991-11-01), Schneider et al.
Miller, D. L., "Ultrasonic Detection of Resonant Cavitation Bubbles in a Flow Tube by Their Second-Harmonic Emissions", Ultrasonics Sep. 1981, 217-224.
Kost et al. Ultrasonic Modulated Drug Delivery Systems Polymers in Medicine II Plenum Press New York 387-396.
Brown et al. Transdermal Delivery of Drugs Ann. Rev. Med. 1988 39:221-229.
Santaella et al. Extended in vivo blood circulation time of fluorinated liposomes FEBS 1993 336:481-484.
Gramiak et al., Radiology, "Detection of Intracardiac Blood Flow by Pulsed Echo-Ranging", pp. 415-418 (1971).
Feigenbaum et al., Circulation, "Identification of Ultrasound Echoes from the Left Ventricle by Use of Intracardiac Injections of Indocyanine Green", vol. XL1, pp. 615-621 (1970).
Stelmashok et al., Koordinatsionnaya Khimiya, vol. 3, No. 4, pp. 524-527 (1977) (Russian language version).
Fitzpatrick et al. Metal Ion Catalyzed Decarboxylation: Kinetics and Mechanism fo the Oxidative Decarboxylation of Copper (II) Complexes of Aminomalonic Acid in Aqueous Solution Inorganic Chem. 1974 13:568-574.
Thanassi Aminomalonic Acid: Spontaneous Decarboxylationand reaction with 5-Deoxypyridoxal Biochemistry 1970 9:525-532.
Stelmashok et al. Koordinatsionnaya Khimiya 1977 3:524-527 (English Version).
Jain et al. Introduction to Biological Membranes Ch. 9 192-231 J. Wiley and Sons, NY 1980.
Sigel H. Ed., Metal Ions in Biological Systems: Antibiotics and Their Complexes vol. 19 Marcell Dekker NY 1985.
Nayar et al. Generation of Large Unilamellar Vesicles From Long-Chanin Saturated Phosphtidylcholines by Extrusion Technique Biochimica et Biophysica Acta 1989.
Hope et al. Generation of Multilamellar and Unilamellar Phospholipid Vesicles Chem. Phys. of Lipids 1986 40:89-107.
Mattrey et al. Perfluorochemicals as US Contrast Agents for Tumor-Imaging and Hepatosplenography: Preliminary Clinical Results Radiology 1987 163:339-343.
Mattrey et al. Perfluorocytlbromide: A Liver/Spleen-Specific and Tumor Imaging Ultrasound Contrast Material Radiology 1982 145:759-762.
Keller et al. Successful Left Ventricular Opacification Following Peripheral Venous Injection of Sonicated Contrast Agent LV Contrast Echocardiography 1987.
Feinstein et al. Two-Dimensional Contrast Echocardiography I JACC 1984 3:14-20.
Ten Cate et al. Two-Dimensional Contrast Echocardiography II JACC 1984 3:21-27.
Unger et al. Hepatic Metastases: Lipsomal Gd-DTPA-enhanced MR Imaging Radiology 1989 171:81-85.
Deamer et al. Permeability of Lipid Bilayers to Water and Ionic Solutes Chem. Phys. Lipids 1986 40:167-188.
Gutknecht et al. Diffusion of Carbon Dioxide Through Lipid Bilayer Membranes Chemical Abstracts 1977 87:34772q.
Scarpa et al. Cation Permeability of Liposomes as a Function of the Chmical Composition of the Lipid Bilyares Biochimica et Biophysica Acta 1971 241:789-797.
MacNaughton et al. Effects of Gaseous Anesthetics and Inert Gases on the Phase Transition in Smectic Mesophases of Dipalmitoyl Phosphatidylcholine Biochim. et Biophy. Acta 1980 597:193-198.
Tilcock et al. Liposomal Gd-DTPA Radiology 1989 171:77-80.
Mann et al. Formation of Iron Oxides in Unilamellar Vesicles Journal of Colloid and Interface Science 1988 122:326-335.
Anderson et al. Manganese (III) Complexes in Oxidative Decarboxylation of Acids J. Am. Chem. Cos. 1970 92:2450-2460.
Muhlradt et al. Vitamin B6 Analogs New Compounds 1967 10:129-130.
Chapman D. Physiochemical Properties of Phopholipids and Lipid Water Systems Liposome Technology 1984 1:1-19.
Violante et al. Particulate Suspensions as Ultrasonic Contrast Agent
Fritz Thomas A.
Matsunaga Terry
Ramaswami Varadarajan
Unger Evan C.
Wu GuanLi
ImaRx Pharmaceutical Corp.
Kishore Gollamudi S.
LandOfFree
Method of preparing gas and gaseous precursor-filled microsphere does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Method of preparing gas and gaseous precursor-filled microsphere, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Method of preparing gas and gaseous precursor-filled microsphere will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1989362