Method of preparing gamma globulin suitable for intravenous admi

Details Method of preparing gamma globulin suitable for intravenous admi Method of preparing gamma globulin suitable for intravenous admi

1982-09-24

1984-10-09

Shapiro, Lionel M.

Drug, bio-affecting and body treating compositions

Lymphokine

260112R, 260112B, A61K 3900, A61K 4502, A23J 0000, C07G 700

Patent

active

044761090

ABSTRACT:
A method of preparing gamma globulin suitable for intravenous administration comprising a first step of treating a supernatant liquid separated from human blood plasma with ethanol under conditions of a pH of 5.5 to 6.5, an ethanol concentration of 30 to 35%, and a protein concentration of 1 to 2% by weight.

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Oncley, "The Separation of the Antibodies, Isoagglutinins, Prothrombin, Plasminogen and .beta..sub.1 -Lipoprotein into Subfractions of Human Plasma", Feb., 1949, vol. 71, pp. 541-550.
Cohn, "Preparation and Properties of Serum and Plasma Proteins. IV. A System for the Separation into Fractions of the Protein and Lipoprotein Components of Biological Tissues and Fluids", Mar. 1946, vol. 68, pp. 459-475.

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