Drug – bio-affecting and body treating compositions – Fermentate of unknown chemical structure – Having a known elemental analysis
Patent
1980-03-05
1982-07-27
Rosen, Sam
Drug, bio-affecting and body treating compositions
Fermentate of unknown chemical structure
Having a known elemental analysis
260112R, 424177, A61K 3514
Patent
active
043417647
ABSTRACT:
Methods are disclosed for obtaining fibronectin and antihemophilic factor in commercial quantities from blood plasma. In the disclosed methods a blood plasma fraction containing fibronectin and antihemophilic factor is isolated from blood plasma and then solubilized in an aqueous medium. The solution is acidified and chilled at a temperature sufficient to form an acid-chill precipitate containing a major proportion of the fibronectin and a solution containing a major proportion of the antihemophilic factor of the blood plasma fraction. Fibronectin and antihemophilic factor are then isolated respectively from the precipitate and solution.
REFERENCES:
patent: 4210580 (1980-07-01), Amrani
Vuento-Biochem. J.-vol. 183, (Nov. 1979), pp. 331-333 & 336.
Stathakis-Chem. Abst., vol. 89, (1978), p. 18609c.
Rock et al.-Chem. Abst., vol. 93, (1980), pp. 155,766y.
Lundblad John L.
Schneider Phillip M.
Wallace Donald G.
Cutter Laboratories, Inc.
Leitereg Theodore J.
Rosen Sam
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