Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Patent
1992-12-24
1995-05-23
Naff, David M.
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
264 4, 264 47, 424451, 425382R, 4253822, 435178, 435179, 43524022, 43524023, 530817, C12N 1104, C12N 500, B01J 1302, A61K 948
Patent
active
054181542
ABSTRACT:
Elongated seamless capsules containing biological material are prepared by a method in which a coagulant, which includes a cell suspension or other biologically active factor, and a polymeric casting solution are extruded through a common extrusion port having at least two concentric bores, such that the coagulant is extruded through the inner bore and the polymeric casting solution is extruded through the outer bore. The method involves initiating extrusion of the coagulant subsequent to initiating delivery of the casting solution through the respective bores to form a capsule having a curved and smooth leading edge shape. Delivery of the coagulant is then shut off, and extrusion of the casting solution is terminated either immediately or after some predetermined time.
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Aebischer Patrick
Doherty Edward J.
Mills John F.
Tresco Patrick A.
Wahlberg Lars
Brown University Research Foundation
Elrifi Ivor R.
Haley, Jr. James F.
Naff David M.
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