Method of preparing D-.alpha.-amino acids

Details Method of preparing D-.alpha.-amino acids Method of preparing D-.alpha.-amino acids

1990-05-25

1990-12-25

Lilling, Herbert J.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing alpha or beta amino acid or substituted amino acid...

435 43, 435107, 435108, 435114, 435115, 435116, 435245, 435822, C12P 1304

Patent

active

049802844

ABSTRACT:
A substantial elevation of the space-time yield is achieved in the preparation of D-.alpha.-amino acids by means of the biotransformation of hydantoins which are monosubstituted in the 5-position in an aqueous medium in the presence of cells of the microorganism Agrobacterium radiobacter if the biotransformation is carried out under a elevated pressure at the start of the reaction. A further improvement results if this elevated pressure is maintained for a period of at least 16 hours, then removed and the biotransformation continued at atmospheric pressure.

REFERENCES:
patent: 4211840 (1980-07-01), Nakamori et al.
patent: 4237227 (1980-12-01), Yamada et al.
patent: 4242452 (1980-12-01), Yamada et al.
patent: 4248967 (1981-02-01), Viglia et al.
patent: 4312948 (1982-01-01), Olivieri et al.
patent: 4613691 (1986-09-01), Mirviss et al.
Biotech & Bioeng, vol. 23(10) pp. 2173-2183 (1981) Bibiau CA 96-4917(1) Olivieri et al.

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