Method of preparing controlled-release preparations for biologic

Details Method of preparing controlled-release preparations for biologic Method of preparing controlled-release preparations for biologic

1990-06-18

1992-09-29

Lovering, Richard D.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

264 41, 424 45, 424 84, 424498, 424501, 4284022, 436829, 514963, 514965, 514966, 514974, A61K 9127, A61K 3722, B01J 1306

Patent

active

051512726

ABSTRACT:
A method and product for preparing a controlled-release composition are provided. The method comprises formation of a mixture containing at least one amphiphilic substance capable of forming a liquid crystalline phase, in contact with a liquid selected from the group consisting of water, glycerol, ethylene glycol, propylene glycol and mixtures thereof. The method includes a step of providing in such mixture a bioactive material. Preferred controlled-release compositions include an alkylbetaine zwitterionic surfactant therein.

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