Method of preparing comtrolled release fenofibrate

Details Method of preparing comtrolled release fenofibrate Method of preparing comtrolled release fenofibrate

1988-10-12

1990-10-09

Lowe, James

Plastic and nonmetallic article shaping or treating: processes

Forming articles by uniting randomly associated particles

Stratified or layered articles

264114, 264121, 264122, 264123, 264131, 424439, 424471, 424479, 424482, 424490, 4274121, B28B 1106, A61K 922

Patent

active

049618903

ABSTRACT:
A process for preparing a controlled release medicine containing fenofibrate in an intermediate layer in the form of cyrstalline microparticles included within pores of an inert matrix prepared by a process involving the sequential steps of dampening said inert core with a solution based on said biner, then projecting said fenofibrate microparticles in a single layer onto said dampened core, and thereafter drying before said solution based on said binder dissolves said fenofibrate microparticles and repeating said three steps in sequence until said intermediate layer is formed.

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