Method of preparing calibration curve for quantitative...

Details Method of preparing calibration curve for quantitative... Method of preparing calibration curve for quantitative...

2005-08-25

2010-10-05

Winakur, Eric F (Department: 3768)

Surgery

Diagnostic testing

Measuring or detecting nonradioactive constituent of body...

C600S310000

Reexamination Certificate

active

07809416

ABSTRACT:
A method of non-invasively determining a concentration of an in-vivo component such as blood sugar level (glucose) of a subject is provided. An absorption spectrum of the subject is measured by use of near-infrared light. The concentration of the in-vivo component is determined by use of the absorption spectrum of the subject and a calibration curve. The calibration curve is prepared by determining a plurality of difference absorption spectra that are differences between a plurality of near-infrared absorption spectra of a living body and a reference absorption spectrum selected from the near-infrared absorption spectra, determining a plurality of synthetic absorption spectra, which are obtained by synthesizing each of the difference absorption spectra with a previously measured reference absorption spectrum of the subject, and performing a multivariate analysis with use of the obtained synthetic absorption spectra.

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