Method of preparing biologically active reagents from succinimid

Details Method of preparing biologically active reagents from succinimid Method of preparing biologically active reagents from succinimid

1991-01-25

1994-05-03

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

422 56, 422 57, 428403, 428407, 436170, 436528, 436531, 436533, 436534, 436536, 436538, 436541, 524548, 524900, 525279, G01N 33531, G01N 33543, G01N 33546

Patent

active

053087496

ABSTRACT:
Biologically active reagents are prepared from particles of copolymers having highly active succinimid groups. The reagents are prepared by covalently attaching biologically active substances, for example antibodies, to the particles, directly or indirectly through amide groups by displacement of highly active succinimid groups on the particle surface. These reagents are used to advantage in analytical elements, methods for the detection of specific binding ligands (such as immunological species) and immunoassays, and in purification methods such as affinity chromatography.

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