Method of preparing biological materials and preparations...

Details Method of preparing biological materials and preparations... Method of preparing biological materials and preparations...

2005-12-13

2005-12-13

Spear, James M. (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S422000, C424S423000, C424S427000, C424S434000, C424S435000, C424S439000, C424S440000, C424S464000, C424S468000, C424S490000, C514S772300, C514S774000, C514S776000, C514S777000, C514S778000, C514S779000, C514S782000

Reexamination Certificate

active

06974594

ABSTRACT:
Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a coating liquid comprising at least one active, a sugar polymer and a water soluble/miscible solvent; (ii) providing a quantity of microparticles comprising at least water soluble gel forming solid particles; (iii) fluidizing said quantity of microparticles within a processing chamber of a of a suitable apparatus to form a fluidized bed of said microparticles; (iv) spraying said coating liquid onto said fluidized bed from beneath the fluidized bed to coat said microparticles therewith under saturated moisture conditions; and (vi) allowing coated microparticles to dry, are described. Also described are compositions and uses.

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