Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Reexamination Certificate
2006-09-21
2010-11-30
Lankford, Leon B (Department: 1651)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
Reexamination Certificate
active
07842305
ABSTRACT:
There is provided a method of preparing biodegradable dual pore polymer scaffolds, comprising the steps of: maintaining a polymer solution containing a biodegradable polymer, an effervescent mixture of carbonate and organic acid, and solvent at a temperature range of −196° C. to ambient temperature so as to evaporate the solvent and produce a polymer sample; and foaming the polymer sample in a mixed solution of water and alcohol.According to the present invention, the pore size of the polymer scaffolds can be easily controlled, and biodegradable polymer scaffolds can be more simply prepared compared to conventional methods such as salt leaching technique, phase separation technique or gas foaming technique. Further, since the biodegradable polymer scaffolds prepared according to the present invention have a high surface area and porosity without formation of skin layer, secretion of toxic substances and remnant phenomenon, they can be advantageously used for regenerating almost all living tissues and organs in tissue engineering.
REFERENCES:
patent: 5223246 (1993-06-01), Kondo et al.
patent: 5723508 (1998-03-01), Healy et al.
patent: 6562374 (2003-05-01), Han et al.
patent: 2006/0147486 (2006-07-01), Kim et al.
patent: 100486367 (2005-04-01), None
Liao et al., J Biomed Mater Res, 2002, vol. 59, p. 676-681.
Van de Witte et al., Journal of Polymer Science: Part B: Polymer Physics, 19996, vol. 34, p. 2569-2578.
Wu et al., J Biomed. Mater. Res., Aug. 2005, vol. 75A, p. 767-777.
Karageorgiou et al. , Biomaterials, Apr. 2005, vol. 26, p. 5474-5491.
Mikos et al., Polymer, 1994, vol. 35, No. 5, Abstract.
Hu et al., J. Biomed. Mater. Res. 2002, vol. 59, p. 563-572.
Ahn Kwang-Duk
Han Dong Keun
Jung Hyun Jung
Park Kwideok
Ariani Kade
Day Jones
Korea Institute Of Science And Technology
Lankford Leon B
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