Method of preparing beta-2',2'-difluoronucleosides

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing saccharide radical

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435191, 435280, 536 24, 536 26, C12P 1940, C12N 906, C07H 1936

Patent

active

049140280

ABSTRACT:
A process for preparing .beta.-2',2'-difluoronucleosides, and a novel intermediate thereto, are disclosed.

REFERENCES:
patent: 4526988 (1985-07-01), Hertel
patent: 4692434 (1987-09-01), Hertel
Montgomery et al., J. Med. Chem. 29, 2389-2392 (1986).
Bennett et al., Mol. Pharmacol. 12, 242-250 (1976).
Secrist et al., J. Med. Chem. 30, 746-749 (1987).
Vorbruggen et al, the Chemical Abstracts 92: 198686u (1980).
Vorbruggen et al, Liebigs Ann. Chem pp. 745-761 (1976).

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