Method of preparing benzothiazepine derivatives

Details Method of preparing benzothiazepine derivatives Method of preparing benzothiazepine derivatives

1982-12-01

1984-03-20

Bond, Robert T.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D28102

Patent

active

044380356

ABSTRACT:
A benzothiazepine derivative of the formula: ##STR1## wherein R is hydrogen or acetyl, is prepared by condensing a compound of the formula: ##STR2## wherein R is the same as defined above, with 2-(diamethylamino)ethyl halide (i) in the presence of potassium hydroxide in acetone; or (ii) in the presence of potassium carbonate in acetone, lower alkyl acetate, a mixture of acetone and water or a mixture of lower alkyl acetate and water.

REFERENCES:
patent: 3562257 (1971-02-01), Kugita et al.
Chemical and Engineering News, vol. 44, No. 15, p. 48, (1966).

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