Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Solid support and method of culturing cells on said solid...
Reexamination Certificate
2008-07-15
2008-07-15
Naff, David M. (Department: 1651)
Chemistry: molecular biology and microbiology
Animal cell, per se ; composition thereof; process of...
Solid support and method of culturing cells on said solid...
C435S325000, C435S357000
Reexamination Certificate
active
07399634
ABSTRACT:
The object of the present invention is to provide a method for preparing a basement membrane comprising extracellular matrices having a function to control morphology, differentiation, proliferation, motility, function expression and the like of cells. This basement membrane is formed by culturing cells having an ability to form a basement membrane on a fibrous collagen matrix coated with a polymer having a sugar chain. This sugar chain coat can localize a receptor which has an activity to accumulate a basement membrane component on the basal surface of the cells.
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Enrico Cagliero, et al., Increased Expression Of Basememt Membrane Components In Human Endothelial Cells Cultured In High Glucose, J. of Clinical Investigation (1988) vol. 82, p. 735-738.
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Joseph El Khoury, et al, Macrophages Adhere To Gluose-Modified Basement Membrane Collagen IV Via their Scavenger Receptors, The Journal of Biological Chemistry, (1994) vol. 269, No. 14, p. 10197-10200.
Herve Emonard, et al., Interactions Between Fibroblasts And A Reconstituted Basement Membrane Matrix, The Journal Of Investigative Dermatology (1987) vol. 89, No. 2, p. 156-163.
Debabrata Ghosh, et al., Functional Differentiation Of Mouse Uterine Epithelial Cells Grown On Collagen Gels Or Reconstituted Basement Membranes, In Vitro Cell. Dev. Biol. (1991) vol. 27A.
K. Jansson, et al., Time-Course For In Vitro Development Of Basement Membrane, Gap Junctions, And Repair By Adult Endothelial Cells Seeded On Precoated ePTFE, Eur. J. Vac. Endovasc. Surg. (1998) vol. 16, p. 334-341.
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Supplementary European Search Report dated Sep. 4, 2007.
Frommer & Lawrence & Haug LLP
Japan Science and Technology Agency
Kowalski Thomas J.
Lu Deborah L.
Naff David M.
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