Method of preparing antithrombogenic medical materials

Details Method of preparing antithrombogenic medical materials Method of preparing antithrombogenic medical materials

1986-08-01

1989-02-21

Kight, John

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

514 56, 514822, 523112, 623 1, 623 11, 623 12, A61F 204, A61M 103

Patent

active

048065951

ABSTRACT:
In a method of preparing an antithrombogenic medical material having a heparinized collagen as an antithrombogenic component, there is provided a method comprising the steps of fixing a protamine to a collagen through a polyepoxy compound, and heparinizing the collagen by fixing heparin to the protamine.

REFERENCES:
patent: 4001200 (1977-01-01), Bonsen et al.
patent: 4690973 (1987-09-01), Noishiki et al.
patent: 4704131 (1987-11-01), Noishiki et al.
Noishiki et al., "A Simple Method to Heparinize Biological Materials," J. of Biomed. Mat. Res., vol. 20, 337-346 (1986).

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